Emeritus Professor Tony Moffat
Position
Emeritus Professor of Pharmaceutical Analysis
Areas of Expertise
Pharmaceutical Analysis, Near-Infrared Spectroscopy, Chromatography, High Performance Liquid Chromatography, Mass Spectrometry, Spectrometry, Forensic Science, Drugs of Abuse, Forensic Toxicology, Validation Protocols in Pharmaceutical Analysis, (especially the Regulatory Requirements), Cannabis as a Medicine.
Biography
Tony Moffat was Head of the Centre for Pharmaceutical Analysis at The School of Pharmacy, University of London. He retired from full-time employment with the University in 2007 and was then appointed Emeritus Professor of Pharmaceutical Analysis. He was previously Chief Scientist at the Royal Pharmaceutical Society of Great Britain.
Before that he was superintendent pharmacist of a community pharmacy, a chief pharmacist in a hospital and worked for 23 years in the Forensic Science Service as Research Co-ordinator (Birmingham Laboratory), Resources Manager (Huntingdon Laboratory), Head of Quality Management (Headquarters, London), Assistant Director (Huntingdon Library) and Head of the Drugs and Toxicology Division (Aldermaston Laboratory).
His awards include the British Pharmaceutical Conference Science Award, Society of Analytical Chemistry Silver Medal, Joint winner of the Buchi Award, Honorary Fellowship of The School of Pharmacy, Charter Gold Medal of the Royal Pharmaceutical Society of Great Britain and the Medal of the Academy of Pharmaceutical Sciences.
Research Interests
His main interest has been the development of near-infrared (NIR) spectroscopic methods of analysis both of raw materials and intact tablets. Close collaboration with the British pharmaceutical industry has ensured that the methods are those that are required and can be adopted by them in their quality control laboratories and production sites across the world.
More recently, the development of fast, non-destructive methods for identifying counterfeit medicines has received regulatory interest both nationally and internationally.
He has supervised 22 PhD students and 6 postdoctoral researchers at The School. He has 333 publications: 7 books, 181 full research papers, 104 short communications and 41 other publications.
Selected Publications |
Clarke’s Analysis of Drugs and Poisons, Third Edition, Moffat A.C., Osselton M.D. and Widdop, B. Editors, 2004, Pharmaceutical Press, London. Volume 1 - 648 pages and Volume 2 - 1632 pages.
Smith, M.R., Jee, R.D., Moffat, A.C., Rees, D.R. and Broad, N.W. A procedure for calibration transfer between near-infrared instruments – a worked example using a transmittance single tablet assay for piroxicam in intact tablets, Analyst, 129, 806-816 (2004).
Yoon, W.L., Jee, R.D., Charvill, A., Lee, G. and Moffat, A.C. Application of near-infrared spectroscopy to the determination of the sites of manufacture of proprietary products, Journal of Pharmaceutical and Biomedical Analysis, 34, 933-944 (2004).
O’Neil, A.J., Jee, R.D. and Moffat, A.C. Measurement of the percentage volume particle size distribution of powdered microcrystalline cellulose using reflectance near-infrared spectroscopy, Analyst, 128, 1326-1330 (2003).
Clarke, F.C., Jamieson, M.J., Clark, D.A., Hammond, S.V., Jee, R.D. and Moffat, A.C. Chemical Image fusion. The synergy of FT-NIR and Raman mapping microscopy to enable a more complete visualization of pharmaceutical formulations. Analytical Chemistry, 73, 2213-2220 (2001).