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The School of Pharmacy, University of London



Professor Michael Heinrich - Publications List (2004 – 2009)

A.  Textbooks and edited volumes

Heinrich, M., Barnes, J., Gibbons, S., Williamson, E. (2004) Fundamentals of Pharmacognosy and Phytotherapy. Churchill Livingstone, Edinburgh.

Heinrich. M. (guest editor) (2005) Themed issue of the Journal of Pharmacy and Pharmacology ‘Drugs of Neotropical Origin’. Journal of Pharmacy and Pharmacology 57 (9-September)

Heinrich, M., W. Müller and, C. Galli, eds. (2006) Local Foods from the Mediterranean and New Nutraceuticals Forum of Nutrition 59. Karger. Basel, CH. ISBN 3–8055–8124–6 

B.   Peer-reviewed Publications

B1. Ethnobotany and related fields

Andrade-Cetto, A., J. Becerra, E. Martínez-Zurita, P. Ortega Larrocea and M. Heinrich (2006) Disease-consensus Factor as a tool of selecting potential hypoglycemic plants in Chikindzonot, Yucatán, México. Journal of Ethnopharmacology 107: 199-204 (doi: 10.1016/j.jep.2006.03.005)

Edwards, S., S. Nebel and M. Heinrich (2005) Methodological and epidemistiological considerations on the use of questionaires in Ethnopharmacology. Journal of Ethnopharmacology 100: 30–36. doi:10.1016/j.jep.2005.05.026

Edwards, S. and M. Heinrich (2006) Socio-cultural concepts of health, sickness and healing from within an Aboriginal community of far North Queensland, Australia. Environment, Development and Sustainability 8: 569 -583.  DOI: 10.1007/s10668-006-9056-1

Freymann, H., T. Rennie, I. Bates, S. Nebel and M. Heinrich (2006) Knowledge and use of herbal medical products and other CAM among undergraduate students at a British School of Pharmacy. Pharmacy World and Science 27. DOI 10.1007/s11096-005-2221-z

Giovannini, P. and M. Heinrich (2009) Xki yoma’ (our medicine) and xki tienda (patent medicine)—Interface between traditional and m odern medicine among the Mazatecs of Oaxaca, Mexico . Journal of Ethnopharmacology 121: 383 – 199. (doi:10.1016/j.jep.2008.11.003)

Heinrich, M. and José Prieto-Garcia (2008) Diet and Healthy Ageing 2100: Will we globalise local knowledge systems? Ageing Research Reviews 7: 249–274.DOI: 10.1016/j.arr.2007.08.002

Heinrich, M. J. Kufer und M. Leonti (2005) Ethnobotanik und Pharmaziegeschichte – gemeinsame Herausforderungen und Aufgaben. Zeitschrift für Phytotherapie 26 (2): 54 – 60.

Heinrich, M., Pieroni A. and Bremner P. (2005) Medicinal Plants and Phytomedicines. IN: 'The Cultural History of Plants'. Consulting Editor: Ghillean Prance, Scientific Editor: M. Nesbitt. New York. Routledge (Taylor and Francis), pp. 205 – 238.

Heinrich, M. M. Leonti, S. Nebel and W. Peschel (2005) 'Local Food – Nutraceuticals': An Example of a Multidisciplinary Research Project on Local Knowledge. Journal of Pharmacology and Physiology 56 (Suppl.): 5-22

Heinrich, M., M. Pardo-de-Santayana, J. Kufer and M. Leonti (2006) Ethnobotany and ethnopharmacology – Interdisciplinary links with the historical sciences. Journal of Ethnopharmacology 107: 157-160. DOI 10.1016/j.jep.2006.05.035

Heinrich, M., S. Edwards,  D. E. Moerman, M. Leonti (2009) Ethnopharmacological Field Studies: A Critical Assessment of their Conceptual Basis and Methods. Journal of Ethnpharmacology 124: 1 – 17 (doi:10.1016/j.jep.2009.03.043)

Kufer, J. and M. Heinrich (2007) Food for the Rain Gods. Cacao in Ch'orti' ritual. IN: McNeil., C., ed. The Origin of Chocolatl. Cacao in the Americas. U. Florida Press.

Kufer, J., H. Förther, E. Pöll and M. Heinrich (2005) Ethnobotany of the Ch'orti'. Journal of Pharmacy and Pharmacology 57: 1127–1152. DOI: 10.1211/jpp.57.9.0008

Kufer, J., N. Grube and M. Heinrich (2006) The cultural significance of use of Theobroma cacao in Eastern Guatemala – a multidisciplinary perspective. Environment, Development and Sustainability 8: 597–608. DOI 10.1007/s10668-006-9046-3

Leonti, M., S.Nebel, D. Rivera,  M. Heinrich (2006) Wild gathered food in the European Mediterranean: A Comparison. Economic Botany 60 (2): 130 – 142.

Nebel. S. and M. Heinrich (2009) Ta Chòrta: A Comparative Ethnobotanical-Linguistic Study of Wild Food Plants in a Graecanic Area in Calabria, Southern Italy. Economic Botany 63: 78 - 92 (DOI: 10.1007/s12231-008-9069-9)

Nebel, S., A. Pieroni and M Heinrich (2006) Ta chòrta: wild edible greens used in the Graecanic area in Calabria, Southern Italy. Appetite (47 (3): 333-342. doi:10.1016/j.appet.2006.05.010

Pardo-de-Santayana, M., J. Tardío, M. Heinrich, A. Touwaide and R. Morales (2006) Plants in the works of Cervantes. Economic Botany 60 (2): 159 – 181.

Pieroni, A., S. Nebel, R.F. Santoro and M. Heinrich (2005) Food for two seasons: Culinary uses of non-cultivated local vegetables and mushrooms in a south Italian village. International Journal of Food Sciences and Nutrition 56(4): 245-272.

Rivera, D, C. Obón, C. Inocencio, M. Heinrich, A. Verde, J. Fajardo and R. Llorach (2005) The ethnobotanical study of local Mediterranean food plants as medicinal resources in Southern Spain. Journal of Pharmacology and Physiology 56 (Suppl.): 97 – 114

Rivera, Diego, Alonso. Verde, José Fajardo, Cristina Inocencio, Concepción Obón, M. Heinrich (eds), (2006) Guía etnobotánica de los alimentos locales recolectados en la provincia de Albacete. Instituto de Estudios Albacetenses ‘Don Juan Manuel’ de la Excma. Diputación de Albacete. Alabacete, Spain. Serie Estudios No. 167.Alabacete ISBN: 84-95394-92-8.

 Rivera, D, C. Obón, C. Inocencio, M. Heinrich, A. Verde, J. Fajardo and R. Llorach (2005) The ethnobotanical study of local Mediterranean food plants as medicinal resources in Southern Spain. Journal of Pharmacology and Physiology 56 (Suppl.): 97 – 114.

Rivera, D., C. Obón, C. Inocencio, M. Heinrich, A. Verde, J. Fajardo and J. A. Palazón (2007) Ethnobotanical study of gathered food plants of Castilla-La Mancha, Spain using multivariate analysis. Economic Botany 61 (3): 269–289

Sandhu, Davinder S. and M. Heinrich (2005) The use of health foods, spices and other botanicals with the Sikh community in London. Phytotherapy Research 19: 633 – 642. DOI:10.1002/ptr.1714

Vallejo, J.R., D. Peral, , P. Gemio,  M.C.Carrasco, M. Heinrich & M Pardo-de-Santayana (2009) Atractylis gummifera and Centaurea ornata in the Province of Badajoz (Extremadura, Spain) - ethnopharmacological importance and toxicological risk.  Journal of Ethnopharmacology  126: 366 – 370.

B.2. Bioactive natural products

Andrade-Cetto, A.  and M. Heinrich (2005) Mexican plants with hypoglycaemic effect used in the treatment of diabetes. Journal of Ethnopharmacology 99 (3): 325-348.

Appendino, G., F. Bianchi, A. Bader, C. Campagnuolo, E. Fattorusso, O. Taglialatela-Scafati, M. Blanco-Molina, A. Macho, B.L. Fiebich, P.M. Bremner, M.Heinrich, M. Ballero and E. Muñoz (2004) Coumarins from Opopanax chironium. New dihydrofuranocoumarins and Differential Induction of Apoptosis by Imperatonine and Heraclenine. Journal of Natural Products 67 (4): 532 – 536.

Beha, E., A. Jung, J. Wiesner, H. Rimpler, M. Lanzer and M. Heinrich (2004) Antimalarial Activity of Abutilon grandiflorum G. DON - a traditional Tanzanian Medicinal Plant. Phytotherapy Research 18: 236 – 240.

Bremner, P. and M. Heinrich  (2005) Anti-Inflammatory Natural Products – Targeted Modulators of the Nuclear Factor-kB Pathway. Phytochemistry Review 4(1): 21 – 37. DOI: 10.1007/s11101-004-6000-6

Bremner, P.D., H. Birkmayer, S. Tang, E. Muñoz-Blanco, B. Fiebich, D. Rivera and M. Heinrich (2004) NF-kB Modulators from Bupleurum fruticosum. Planta medica 70: 914 –917.

Bremner P., Rivera, D., Calzado M.A., Obón C., Inocencio C.,  Beckwith C., Fiebich B.L., Muñoz E., and   Heinrich M. (2009) Assessing Medicinal Plants from Southeastern Spain for Potential Antiinflammatory Effects Targeting Nuclear Factor-Kappa B and other Pro-inflammatory Mediators. Journal of Ethnopharmacology 124 (2009) 295–305

Chandrasekera, Dh. H., K J. Welham, D. Ashton, R. Middleton and M. Heinrich (2005) Quantitative analysis of the major constituents of St. John’s wort with HPLC-ESP-MS. Journal of Pharmacy and Pharmacology 57: 1645-1652. DOI: 10.1211/jpp.57.12.0015

Gómez – Castellanosa, J. R., J. M. Prieto, and M.Heinrich (2009) Red Lapacho Tea (Tabebuia impetiginosa) – a global ethnopharmacological commodity? Journal of Ethnopharmacology 121: 1- 13.

Heinrich, M (2005) Una visión de la fitoquímica desde Europa (La columna de Michael Heinrich). BLACPMA [Boletín Latinoamericana y del Caribe de plantas medicinales y aromáticas] 4(3): 47

Heinrich, M. (2005) Challenges and Threats to Interdisciplinary Medicinal Plant Research. IN: Zahora, Yaniv. Handbook of Medicinal Plants. Binghampton, New York (USA), Haworth Pr.

Heinrich, M and P. Bremner (2006) The role of ethnobotany for anti-cancer drug development. Current Drug Targets 7: 239-246   

Heinrich, M. (2008) Ethnopharmacy and natural product research - multidisciplinary opportunities for research in the metabolomic age. Phytochemistry Letters 1: 1-5.

Heinrich, M and Teoh, H.L. (2004) Galanthamine from Snowdrop – the Development of a Modern Drug Against Alzheimer's Disease from Local Caucasian Knowledge. Journal of Ethnopharmacology 92: 147 – 162.

Heinrich, M and P. Bremner (2006) The role of ethnobotany for anti-cancer drug development. Current Drug Targets 7: 239-246 

Heinrich, M., B.Heneka, B., A. Ankli, H. Rimpler, O. Sticher and Th. Kostiza (2005) Antisecretory and Antispasmodic activity of polymethoxylated flavonoids from Casimiroa tetrameria. Journal of Pharmacy and Pharmacology 57: 1081-1085

Heinrich M, Maryam Modarai, Andreas Kortenkamp (2008) Herbal extracts used for upper respiratory tract infections: Are there clinically relevant interactions with the Cytochrome P450 enzyme system? Planta medica 74: 657 – 660 (DOI: 10.1055/s-2008-1034292)

Heinrich, M., J. Chan, S. Wanke, Ch. Neinhuis and M.S.S. Simmonds (2009) Local Uses of Aristolochia species and content of Aristolochic Acid 1 and 2 –  a global assessment based on bibliographic sources. Journal of Ethnopharmacology 125: 108 – 144.

Heneka, B., H. Rimpler, A. Ankli, O. Sticher, S. Gibbons and M. Heinrich (2005) Polymethoxylated Flavonoids and a Furanocoumarin from Casimiroa tetrameria. Phytochemistry 66: 649 – 652  

Jacobo-Herrera, P.D. Bremner, S. Gibbons M. Gupta, S. Muñoz and M. Heinrich (2006) Physalins from Withania frutescens (Solanaceae) as inhibitors of the NF-B cascade Journal of Natural Products 69 (3): 328 – 331. DOI: 10.1021/np050225t

Jacobo-Herrera, N., N. Vartiainen, P. Bremner, S. Gibbons, J. Koistinaho and M. Heinrich  (2006) NF-kappaB Modulators from Valeriana officinalis. Phytotherapy Research 20 (10): 917 – 919. DOI: 10.1002/ptr.1972

Loboda, A., J. Cisowski, A., Zarebski, A. Jazwa, D. Rivera, M. Heinrich and J. Dulak (2005) Effect of Plant Extracts on Angiogenic Activities of Endothelial Cells and Keratinocytes. Journal of Pharmacology and Physiology 56 (Suppl.1): 125 – 137.

Macho A., M. Blanco-Molina, P. Spagliardi, G. Appendino, P. Bremner, M. Heinrich, B.L. Fiebich, E. Munoz. (2004) Calcium Ionophoretic and Apoptotic Effects of Ferutinin in the Human Jurkat T-cell line. Biochemical Pharmacolology 68(5): 875-83.

Marquez N., R. Sancho, M. Ballero, P. Bremner, G. Appendino, B.L. Fiebich, M. Heinrich, E. Munoz. (2004) The dietary Furanocoumarin Imperatonin Inhibits T-cell Proliferation by Targeting the Transcription Factor NF-AT. Planta medica 70(11): 1016-1021.

Mensah, A.Y., P. J. Houghton, R. A. Dickson, T. C. Fleischer, M. Heinrich, P. Bremner (2006) In Vitro evaluation of effects of two Ghanaian plants relevant to wound healing Phytotherapy Research 20 (11): 941-944. DOI: 10.1002/ptr.1978

Modarai, M., J. Gertsch, A. Suter, M. Heinrich, A. Kortenkamp (2007) Cytochrom e P450 inhibitory action of Echinacea preparations differs widely and co-varies with alkylamide content. Journal of Pharmacy and Pharmacology 59: 567–573. DOI 10.1211/jpp.59.4.0012

Modarai, M., Suter A., A. Kortenkamp,  M. Heinrich, (2010) Metabolomic profiling of liquid Echinacea medicinal products inhibiting  Cytochrome P450 3A4 (CYP3A4). Planta medica in press

Modarai, M., E. Silva, A. Suter, M. Heinrich, and Andreas Kortenkamp (2010)    Safety of Herbal Medicinal Products: Echinacea and selected alkylamides do not induce CYP3A4 mRNA expression.eCAM (Evidence Based Complementary and Alternative Medicine) in press

Mukherjee, Pulok K., Venkatesan Kumar, M.Heinrich (2008) The Ayurvedic medicine Clitoria ternatea - from traditional use to scientific assessment. Journal of Ethnpharmacology 120: 291 – 391.

Mukherjee, Pulok K., Debajyoti Mukherjee, M. Venkatesh, S. Rai and Michael Heinrich (2009) The Sacred Lotus (Nelumbo nucifera) – Phytochemical and Therapeutic Profile. Journal of Pharmacy and Pharmacology  61: 407 – 422.

Obolskiy, Dmitriy, Ivo Pischel, Nisarat Siriwatanametanon, M. Heinrich (2009) Garcinia mangostana L. (mangosteen): A phytochemical and pharmacological review. Phytotherapy Research 27: 1047 – 1065. DOI: 10.1002/ptr.2730

Politi M., W. Peschel, N. Wilson, M. Zloh, J.M. Prieto, and Heinrich M. (2008) Cannabis water extracts and tinctures analysed by NMR spectroscopy; different strategies to reduce the content of D9-THC. Phytochemistry 69: 562–570 (doi:10.1016/j.phytochem.2007.07.018)

Politi M, M  Zloh, M.E Pintado, P.M.L  Castro, M Heinrich, J.M . Prieto (2009) Direct metabolic fingerprinting of commercial herbal tinctures by Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS). Phytochemical Analysis 20: 328 – 334.

Simonsen, H.T, A. Adsersen, P. Bremner, M. Heinrich, U W. Smitt, J.W. Jaroszewski (2004)        Antifungal Constituents of Melicope borbonica. Phytotherapy Research 18 (7): 542-545

Strzelecka, M., M. Bzowska, J. Kozie, B. Szuba, O. Dubiel, D. Rivera, M. Heinrich, J. Bereta (2005) Anti-inflammatory effects of some traditional Mediterranean Diet Plants. Journal of Pharmacology and Physiology 56 (Suppl. 1):139 - 156

The Local Food-Nutraceutical Consortium [M. Heinrich, M.Leonti, S. Nebel S, W. Peschel, A. Pieroni, F. Smith, D. Rivera, C. Obon, C. Inocencio, A. Verde, JFajardo, R. Llorach, W.E. Muller, G.P. Eckert, S. Schaffer*, S. Schmitt-Schillig, S. Antonopoulou, Z. Kypriotakis, Y Manios, T. Nomikos, A. Kaliora, L. Sidossis, C. Galli, F. Visioli, S. Grande, P. Bogani, A. de Saizieu, B. Fluhmann, D. D'Orazio, A. Fowler, A.Koj, J. Bereta, J. Dulak, A. Guzdek, M. Kapiszewska (corresponding author: S. Schaffer, coordinator M. Heinrich)] (2005) Local Mediterranean diets: a joint ethnobotanical and phyto-pharmacological approach. Pharmacological Research 52: 353–366. doi:10.1016/j.phrs.2005.06.005  

B.3. Other publications and output (selection)

Barnes, J., P. Bremner, S. Gibbons, J. D. Phillipson and M. Heinrich (2005) Pharmacognosy at the Square – the Past, Present and Future. Pharmaceutical Journal 274: 552 – 554

Heinrich, M. (2004) Galanthamine from Snowdrop. Pharmaceutical Journal 273 (No 7330): 905-906.

Heinrich, M. (2004) Medical knowledge of the Maya (Heilwissen der Maya), documentary [film on our ethnobotanical research in México] in the series ‘Healing knowledge’/Heilwissen. Mainz (DE). ZDF. Broadcasted 21.3. 2004; director: Andreas Orth.

Heinrich, M. (2005) Disseminating Local Knowledge– Diseminar conocimiento local. Preface to / prefacio para Fajardo, J., A. Verde, D. Rivera y C. Obón. 'Material Didactico para escuelas secundarias de Albacete '.

Heinrich, M. (2005) Galantamin – Vom Schneeglöckchen zum Alzheimer Medikament. Pharmazeutische Zeitung 150: 20 – 25.

Heinrich, M (2005)  Standardized extracts of Cannabis for treatment of arthrtis and migraine. Bioforum 9 (7): 28-30.

Zaman, Nuruz and M. Heinrich (2005) Biodiversity uncovered [Editorial]. StudentBMJ 13: 354

B4. Selected older publications

Bork, P.M., Bacher, S., Schmitz, M.L., Kaspers, U. and Heinrich, M. (1999) Hypericin as an non-anti-oxidant inhibitor of NF-kappa B. Planta medica 65, 297-300. 

Bork, P.M., Schmitz, M.L., Kuhnt, M., Escher, C. and Heinrich, M. (1997) Sesquiterpene Lactone containing Mexican Indian medicinal plants and pure Sesquiterpene Lactones as potent inhibitors of Transcription Factor kappa B (NF-kappa B). FEBS-Letters 402, 85-90.

Bremner, P. and Heinrich, M. (2002) Natural Products as modulators of the NF-kappa B-pathway. Journal of Pharmacy and Pharmacology 54: 453-472.

Cox, P.A., Heinrich, M. (2001) Ethnobotany and drug development. Pharmaceutical News 8, 55-59.

Fiebich, B.L., Heinrich, M., Hiller, K.O. and Kammerer, N. (2001). Inhibition of TNF-á synthesis in LPS-stimulated primary human monocytes by Harpagophytum extract SteiHap 69. Phytomedicine 8, 28-30.

Fiebich, B.L., Lieb, K., Engels, S. and Heinrich, M. (2002) Inhibition of LPS-induced p42/44 MAP kinase activation and iNOS/NO synthesis by parthenolide in rat primary microglial cells. Journal of  Neuroimmunology 132, 18-24.

Heinrich, M. (2000) Ethnobotany and its role in drug development. Phytotherapy Research 14, 479-488.

Heinrich, M. (2001) Ethnobotanik und Ethnopharmazie. Eine Einführung. Wissenschaftliche Verlagsgesellschaft, Stuttgart.

Heinrich, M. (2003) Ethnobotany and Natural Products: The search for new molecules, new treatments of old diseases or a better understanding of indigenous cultures? Current Topics in Medicinal Chemistry 3, 29-42

Heinrich, M. and Gibbons, S. (2001) Ethnopharmacology in drug discovery: an analysis of its role and potential contribution. Journal of Pharmacy and Pharmacology 53, 425-432.

Heinrich, M., Ankli, A., Frei, B., Weimann, C. and Sticher, O. (1998) Medicinal plants in Mexico: Healers consensus and cultural importance. Social Science and Medicine 47, 1863-875.

Heinrich, M., Bork, P.M., Schmitz, M.L., Rimpler, H., Frei, B. and Sticher, O. (2001) Phaeophorbid A from Solanum diflorum interferes with NF-kappa B activation. Planta medica 67, 156-157.

Heinrich, M., Robles, M., West, J.E., Ortiz de Montellano, B.R. and Rodriguez, E. (1998) Ethnopharmacology of Mexican Asteraceae (Compositae). Annual Review of Pharmacology and Toxicology 38, 539-565.

Leonti, M., Vibrans, H., Sticher, O. and Heinrich, M. (2001) Ethnopharmacology of the Popoluca, México: an evaluation. Journal of Pharmacy and Pharmacology 53, 1653-1669.

Leonti, M., Sticher, O. and Heinrich, M. (2002) Medicinal Plants of the Popoluca, México: organoleptic properties as indigenous selection criteria. Journal of Ethnopharmacology 81, 307-315.

Leonti, M., F. Ramirez-R., Sticher, O. and Heinrich, M. (2003) Medicinal Floraof the Popoluca, México: A botanico-systematical perspective. Economic Botany  57, 218-230.

Leonti, M., Sticher, O. and Heinrich, M. (2003) Antiquity of Medicinal Plant Usage in two Macro-Mayan Ethnic Groups. Journal of Ethnopharmacology 88: 119-124. Doi:10.1016/S0378-8741(03)00188-0

Pieroni, A., Nebel, S., Quave, C., Munz, H. and Heinrich, M. (2002) Ethnopharmacology of Liakra: Traditional, weedy vegetables of the Arbëreshë of the Vulture area in southern Italy. Journal of Ethnopharmacology 81,165-185.

Tang, S. C. Schlage, A. Kortenkamp, A. Gray, S. Gibbons and Heinrich, M. (2003) Biflavonoids with cytotoxic and immunomodulatory activity from Ochna macrocalyx. Planta medica 69, 247-253.

 

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