Position

Research Fellow in the Department of Pharmaceutics, & the Centre for Paediatric Pharmacy Research

Areas of Expertise

Drug Delivery, Formulation, Biopharmaceutics, Novel Drug Delivery Systems, Microparticular Systems (Microparticles & Nanoparticles), Cell Culture

Biography

Mine Orlu Gul is the Formulation Research Fellow for the London-South East, North Central & East (SENCE) Local Research Network of the UK Medicines for Children Research Network (MCRN, based in the Department of Pharmaceutics & Centre for Paediatric Pharmacy Research at the School of Pharmacy, University of London. She studied pharmacy in Istanbul University, Faculty of Pharmacy, Turkey and qualified as a pharmacist in 2001. She received an MSc on the subject of colon targeted microspheres in 2003, followed by a PhD about fluorescently-labelled nanoparticles and their interaction with lung cells in 2008, both at the Department of Pharmaceutical Technology, Istanbul University, Faculty of Pharmacy. During her PhD studies, she held a 1-year visiting scientist post on cell culture techniques at King`s College London funded by Marie Curie Host Fellowship for Early Stage Training in the 6th Framework Programme of the European Commission. In respect to this, she was awarded an additional professional qualification, Euro-PhD in Advanced Drug Delivery, certified by Galenos Network & Saarland University, Saarbrücken, Germany. Dr. Mine Orlu Gul held post-doctoral research assistant post with Prof. Oya Alpar on vaccine delivery in the School of Pharmacy, University of London.

Research Interests

With an MSc and PhD about novel drug delivery systems, Dr. Orlu Gul main area of research is preparation and characterisation of multiparticulates including their in vitro evaluation on cell culture. At present Dr. Orlu Gul`s research focuses on development of paediatric formulations which enable neonates, infants and children of all ages to have access to safe and effective dosage forms. Additionally, she is particularly interested in the design of multiparticulate modified release preparations for children. She is currently working in projects about the development of oral wafers, investigation of stability of reconstituted extemporaneous preparations and study design of clinical trials.

Selected Publications

Orlu Gul M*, Jones SA, Dailey LA, Nacer H, Ma Y, Sadouki F, Hider R, Araman A, Forbes B. (2009) A poly(vinyl alcohol) nanoparticle platform for kinetic studies of inhaled particles. Inhalation Toxicology. 21(7): 631-640

Cevher E, Taha MAM, Orlu M*, Araman A. (2008) Evaluation of mechanical and mucoadhesive properties of clomiphene citrate gel formulations containing carbomers and their thiolated derivatives. Drug Delivery. 15: 57-67

Orhan Z, Cevher E, Orlu Gul M*, Ozcelik D, Agartan C, Oner F. (2007) Preparation and in vivo evaluation of gelatine implants containing EGF-PLGA microspheres in tendon healing. Acta Pharmaceutica Sciencia. 49: 219-229

Orlu M*, Cevher E, Araman A. (2006) Design and evaluation of colon specific drug delivery system containing flurbiprofen microsponges. Int J Pharm. 318: 103-117

Gungor S, Orlu M*, Ozsoy Y, Araman A. (2003) In vitro studies on sustained release suppository formulations of tiaprofenic acid with sucrose fatty acid ester. Scientia Pharmaceutica. 71: 357-364