Extended Publications List
Antibacterial Plant Natural Products
Smith, E.C.J., Wareham, N., Zloh M. and Gibbons S. (2008). 2β-acetoxyferruginol – a new antibacterial abietane diterpene from the bark of Prumnopitys andina. Phytochemistry Letters (In Press).
Sharma, R.J., Negi, D.S. Gibbons S. and Otsuka H., (2008) Chemical and Antibacterial Constituents of Skimmia anquetelia. Planta Medica (In Press).
Nazemiyeh, H., Rahman, M. M., Gibbons, S., Nahar, L., Delazar, A., Ghahramani, M-A., Talebpoure, A-H. and Sarker, S.D. (2008) Assessment of antibacterial activity of phenylethanoid glycosides from Phlomis lanceolata against multiple-drug resistant (MDR) strains of Staphylococcus aureus. Journal of Natural Medicine, 62: 91-95.
Smith, E.C.J., Williamson, E.M., Kaatz, G.W. and Gibbons, S. (2007). Antibacterials and modulators from immature cones of Chamaecyparis lawsoniana. Phytochemistry 68(2) 210-217.
Rahman, M. M., Gibbons, S. and Gray, A. I. (2007). Isoflavanones from Uraria picta and their antimicrobial activity. Phytochemistry 68, 1692-1697.
O’Donnell G. and Gibbons, S. (2007) Antibacterial Activity of two Canthin-6-one Alkaloids from Allium neapolitanum. Phytotherapy Research 21(7):653-7.
Stavri, M., Mathew, K.T. and Gibbons, S. (2006). Antimicrobial Constituents of Scrophularia deserti. Phytochemistry 67(14), 1530-1533.
O’Donnell, G., Bucar, F. and Gibbons S. (2006). Phytochemistry and Antimycobacterial activity of Chlorophytum inornatum. Phytochemistry 67 (2), 178-182.
Appendino, G., Maxia, L., Bettoni, P., Locatelli, M., Ballero, M., Stavri, M., Gibbons, S. and Sterner, O. (2006) Antibacterial Galloylated Phloroglucinol Glucosides from Myrtle (Myrtus communis) Journal of Natural Products 69(2), 251 - 254.
Ming, Q., Gibbons, S., Stavri, M., Smith, E., Zhou, F-S. and Hu, C-Q. (2006). Antibacterial effects of Hypericum ascyron and Hypericum japonicum Against Multidrug-Resistant (MDR) Staphylococcus aureus. Pharmaceutical Biology 44 (3), 157-159.
Stavri, M., and Gibbons, S. (2005). The Antimycobacterial Constituents of Dill (Anethum graveolens) Phytotherapy Research 19, 938-941.
Smith, E., Williamson, E.M., Zloh, M. and Gibbons S. (2005). Isopimaric acid from Pinus nigra shows activity against multi-drug-resistant and EMRSA strains of Staphylococcus aureus. Phytotherapy Research 19, 538-542.
Gibbons S, (2005) Plants as a source of bacterial resistance modulators and anti-infective agents Phytochemistry Reviews 4 (1), 63-78.<o:p></o:p>
Asres K, Seyoum, A., Veeresham, C., Bucar, F. and Gibbons, S. (2005) Naturally Derived anti-HIV agents. Phytotherapy Research 19, 557-581.
Fragoso-Serrano, M., Gibbons, S. and Pereda-Miranda, R. (2005) Anti-staphylococcal and Cytotoxic Compounds from Hyptis Pectinata. Planta Medica 71(3), 278-80.
Appendino, G., Arnoldi, L. Mercalli, E., Stavri, M., Gibbons, S., Ballero, M. and Maxia, A. (2004). Anti-mycobacterial Coumarins from Sardinian Giant Fennel (Ferula communis) Journal of Natural Products 67(12), 2108-2110.
Gibbons, S. (2004) Anti-Staphylococcal Plant Natural Products. Natural Product Reports 21, 263-277.
Stavri, M. Schneider, R., O’Donnell, G., Lechner, D., Bucar F. and Gibbons S. (2004). The antimycobacterial components of Hops (Humulus lupulus) and their dereplication. Phytotherapy Research 18, 774-776.
Lechner, D., Stavri, M., Oluwatuyi M., Pereda-Miranda, R. and Gibbons, S. (2004). The anti-staphylococcal activity of Angelica dahurica (Bai Zhi). Phytochemistry 64, 331-335.
Stavri, M., Mathew, K.T., Bucar, F. and Gibbons S. (2003). Pangelin, an Antimycobacterial Coumarin from Ducrosia anethifolia. Planta Medica 69, 956-959.
Gibbons, S., Fallah, F. and Wright, C.W. (2003) Cryptolepine hydrochloride: a potent anti-mycobacterial alkaloid derived from Cryptolepis sanguinolenta. Phytotherapy Research 17, 434-436.
Gibbons, S., Leimkugel, J., Oluwatuyi, M. and Heinrich H. (2003) ‘Activity of Zanthoxylum clava-herculis extracts against multidrug resistant methicillin-resistant Staphylococcus aureus (mdr-MRSA)’ Phytotherapy Research 17, 274-275.
Schinkovitz, A., Gibbons, S., Stavri, M., Cocksedge, M.J. and Bucar, F. (2003) Ostruthin: An antimycobacterial coumarin from the roots of Peucedanum ostruthium Koch. Planta Medica 69, 369-371.
Gibbons, S., Ohlendorf, B. and Johnsen, I. (2002) ‘The genus Hypericum - a valuable resource of anti-Staphylococcal leads’ Fitoterapia 73, 300-304.
Bacterial Resistance Modifying Agents
Rahman, M. M., Garvey, M., Piddock L.J.V. and Gibbons, S. (2008). Antibacterial terpenes from the oleo-resin of Commiphora molmol (Engl.). Phytotherapy Research (Accepted).
Stavri, M., Piddock L.J.V. and Gibbons, S. (2007) Bacterial efflux pump inhibitors from natural sources. Journal of Antimicrobial Chemotherapy 59(6):1247-60.
Michalet, S., Cartier, G., Stavri, M., David, B., Mariotte, A-M., Dijoux-Franca, M-G., Kaatz, G.W. and Gibbons, S. (2007). N-Caffeoylphenalkylamide Derivatives as Bacterial Efflux Pump Inhibitors. Bioorganic Medicinal Chemistry Letters 17, 1755-1758.
Pereda-Miranda, R, Kaatz, G. and Gibbons S. (2006) Polyacylated Oligosaccharides from Medicinal Mexican Morning Glory Species as Antibacterials and Inhibitors of Multidrug Resistance in Staphylococcus aureus. Journal of Natural Products 69, 406-409.
Dickson, R.A., Houghton, P. J., Hylands, P.J. and Gibbons S. (2006) Antimicrobial, Resistance modifying effects, Antioxidant and Free radical scavenging activities of Mezoneuron benthamianum Baill., Securinega virosa Roxb. & Wlld. and Microglossa pyrifolia Lam. Phytotherapy Research 20 (1), 41-45.
Cégiéla-Carlioz P, Bessière J-M, <st1:personname>David</st1:personname> B, Mariotte A-M, Gibbons, S. and Dijoux-Franca, M-G. (2005) Osha Essential Oil Modulates Multidrug-Resistance (MDR) in Staphylococcus aureus. Flavour and Fragrance Journal 20, 671-675.<o:p></o:p>
Gibbons, S., Moser, E. and Kaatz, G.W. (2004) Catechin Gallates inhibit Multidrug resistance (MDR) in Staphylococcus aureus. Planta Medica 70 (12), 1240-1242.
Oluwatuyi, M. Kaatz, G. and Gibbons, S. (2004). Antibacterial and Resistance Modifying Activity of Rosmarinus officinalis. Phytochemistry 65, 3249-3254.
Gibbons, S., Oluwatuyi, M. and Kaatz, G.W. (2003) A Novel Inhibitor of Multidrug Efflux Pumps in Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 51, 13-17.
Gibbons, S., Oluwatuyi, M., Veitch, N.C. and Gray, A.I. (2003) Bacterial Resistance Modifying Agents from Lycopus europaeus Phytochemistry 62, 83-87.
Gibbons, S. And Udo, E.E. (2000) 'The effect of reserpine, a modulator of multidrug efflux pumps, on the in-vitro activity of tetracycline against clinical isolates of methicillin resistant Staphylococcus aureus (MRSA) possessing the tet(K) determinant. Phytotherapy Research 14 (2), 139-140.
Mechanisms in multidrug-resistance
Zloh, M. and Gibbons, S. (2007) The role of small molecule – small molecule interactions in overcoming biological barriers for antibacterial drug action. Theoretical Chemistry Accounts 117, 231-238.
Zloh, M., Bucar F. and Gibbons, S. (2007). Quantum Chemical Studies on Structure Activity Relationship of Natural Product Polyacetylenes. Theoretical Chemistry Accounts 117, 247-252.
Zloh, M., Kaatz, G. W. and Gibbons, S. (2004). Inhibitors of Multidrug resistance (MDR) have affinity for MDR substrates. Bioorganic Medicinal Chemistry Letters 14 (4), 881-885.
Zloh, M. and Gibbons S. (2004) Molecular similarity of MDR inhibitors. International Journal of Molecular Sciences 5, 37-47.
Phytochemistry and Pharmacognosy
Stavri, M., Mathew, K.T. and Gibbons, S. (2008). A Novel sesquiterpene skeleton from Pulicaria crispa Natural Product Communications 3 (1), 1-3.
Kladi, M., Vagias, C., Stavri, M., Rahman, M.M., Gibbons, S. and Roussis V. (2008). C15 Acetogenins from the red alga Laurencia glandulifera. Phytochemistry Letters (In Press).
Kontiza, I., Stavri, M., Zloh, M., Vagias, C., Gibbons, S., Roussis, V. (2008). Chemical constituents of marine angiosperm Cymodocea nodosa and their antibacterial activity. Tetrahedron 64 (8), 1696-1702.
Asres, K., Gibbons, S. and Bucar, F. (2006) Radical Scavenging Compounds from Ethiopian Medicinal Plants. Ethiopian Pharmacy Journal 24, 23-30.
Yalçın, F.N., Ersöz, T., Bedir, E., Dönmez, A.A., Stavri, M., Zloh, M., Gibbons, S. and Çalış, I. (2006) Amanicadol, A pimarane type diterpene from Phlomis amanica Vierch. Zeitschrift für Naturforschung B 61b, 1422-1436.
Evans, L., Hedger, J., Brayford, D., Stavri, M., Smith, E., O’Donnell, G., Gray, A.I., Griffith, G. and Gibbons, S. (2006). An antibacterial hydroxy fusidic acid analogue from the mitosporic fungus Acremonium crotocinigenum (Schol-Schwarz) W. Gams. Phytochemistry 67, 2110-2114.
Sharma, R., Negi D.S., Shiu, W.K.P. and Gibbons, S. (2006) Characterization of an insecticidal coumarin from Boenninghausenia albiflora. Phytotherapy Research 20, 607-609.
Abebe Wube, A., Bucar, F., Asres, K., Gibbons S., Adams M., Streit, B., Bodensieck, A., Bauer, R. (2006). Knipholone, a Selective Inhibitor of Leukotriene Metabolism. Phytomedicine 13 (6) 452-456.
Abebe Wube, A., Bucar, F., Gibbons S. and Asres, K. (2005) Sesquiterpenes of Warburgia ugandensis and their Antimycobacterial Activity Phytochemistry 66 (19), 2309-2315.
Wube, A. A., Streit, B., Gibbons, S., Asres, K., Bucar, F. (2005). In vitro 12(S)-HETE inhibitory activities of naphthoquinones isolated from the root bark of Euclea shimperi. Journal of Ethnopharmacology 102 (2), 191-196.
Casely-Heyford, M., Kerr, N. O., Smith, E., Gibbons, S. and Searcey, M. (2005) Antitumour Antibiotics with Potent Activity Against Multidrug-Resistant Staphylococcus aureus: A New Approach to Targeting Resistant Bacteria. Medicinal Chemistry 1 (6), 619-627.
Asres, K., Gibbons, S., Hana, E. and Bucar, F. (2005) Anti-inflammatory Activity of Extracts and a Saponin Isolated from Melilotus elegans. Pharmazie 4, 310-312.
Abebe A, Bucar, F., Asres, K., Gibbons, S. Rattray, L. and Croft, S. (2005) Antimalarial compounds from Kniphofia foliosa roots. Phytotherapy Research. 19 (6), 472-476.
Barnes, J., Bremner, P., Gibbons, S., Phillipson, J.D., Heinrich, M. (2005) <!--[if supportFields]> SEQ CHAPTER \h \r 1<![endif]--><!--[if supportFields]><![endif]-->Pharmacognosy at ‘the Square’ – past, present and future. Pharmaceutical Journal 274, 522-524.
Stavri, M., Ford, C. H. J., Bucar, F., Streit, B., Hall, M. L., Williamson, R. T., Mathew K. T. Gibbons, S. (2005). Bioactive constituents of Artemisia monosperma. Phytochemistry 66, 233-239.
Heneka, B. Rimpler, H. Ankli, A. Sticher, O. Gibbons, S. and Heinrich, M. (2005). A furanocoumarin and polymethoxylated flavonoids from the Yucatec Mayan plant Casimiroa tetrameria. Phytochemistry 66 (6), 649-652.
Barnes, J., Anderson, L. A., Gibbons, S., Phillipson, J. D. (2005). Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) (Moench): a review of their chemistry, pharmacology and clinical properties. Journal of Pharmacy and Pharmacology 57, 929-954.
Delazar, A., Gibbons, S., Kumaraswamy, Y., Nahar, L., Shoeb, M. and Sarker, S.D. (2005). Antioxidant phenylethanoid glycosides from Eremostachys glabra (Lamiaceae). Biochemical Systematics and Ecology 33, 87-90.
Delazar, A., Byres, M., Gibbons, S. Kumarasamy, Y. Nahar, L. Shoeb, M. and Sarker S.D. (2004) Iridoid glycosides from Eremostachys glabra. Journal of Natural Products 67 (9), 1584 -1587.
Stavri, M. Mathew, K.T., Gibson, T., Williamson R.T. and Gibbons, S. (2004) New components of Artemisia monosperma. Journal of Natural Products 67 (5), 892-894.
Schneider I, Gibbons, S. and Bucar, F. (2004) Medicinal plants with inhibitory activity on 12(S)-HETE production in human platelets. Planta Medica 70(5), 471-474.
Wilkinson, J., Whalley, B.J., Baker, D., Pryce, G., Constanti, A., Gibbons, S. and Williamson, E. (2003) Medicinal Cannabis: is D9–tetrahydrocannabinol necessary for all its effects? Journal of Pharmacy and Pharmacology 55, 1687-1694.
Gibbons, S. (2003) An overview of Plant extracts as Potential Therapeutics. Expert Opinion on Therapeutic Patents 13 (4) 489-497.
Tang, S., Bremner, P., Kortenkamp, A., Schlage, C., Gray, A.I., Gibbons, S. and Heinrich, M. (2003) ‘Biflavonoids from Ochna macrolcalyx with cytotoxic and antibacterial activity’ Planta Medica 69, 247-253.
Appendino, G., Bianchi, F., Minassi, A., Sterner, O., Ballero, M. and Gibbons, S. (2002) Oligomeric Acylphloroglucinols from Myrtle (Myrtus communis). Journal of Natural Products 65, 334-338.
Heinrich, M. and Gibbons, S. (2001) Ethnopharmacology in drug discovery: an analysis of its role and potential contribution. Journal of Pharmacy and Pharmacology 53(4), 425-32.
Gibbons S. and Oriowo, M.A. (2001) The Anti-hypertensive effects of Zygophyllum coccineum extracts in Rats. Phytotherapy Research 15, 452-455.
Gibbons, S., Ali-Amine, S., Mathew, K.T., Skelton, B.W., White, A.H. and Gray A.I. (2000) NMR Spectroscopy, X-ray Crystallographic and Molecular Modelling Studies on a new pyranone from Haloxylon salicornicum (Moq.) Bunge ex Boiss. Journal of Natural Products 63(6), 839-40.